Product Details:
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Place of Origin: | Xi'an ,China |
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Brand Name: | Wango |
Certification: | ISO 9001, USP, BP |
Model Number: | WG-00104 |
Payment & Shipping Terms:
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Minimum Order Quantity: | 1000 gram every time |
Price: | FOB price USD 140-160/kilogram |
Packaging Details: | 1kg with double plastic container inside/Aluminum foil bag ; 25kg with double plastic container inside/Fiber drum outside.Or as your request. |
Delivery Time: | 3-5 working days |
Payment Terms: | Western Union, L/C, T/T, MoneyGram |
Supply Ability: | 1000kilogram 0ne month |
Detail Information |
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Appearence: | White Fine Powder | Other Name: | Strontium Ranelate |
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Function: | Treat Osteoporosis | Cas: | 135459-87-9 |
Product Description
ANALYTICAL ITEMS | SPECIFICATION | ANALYTICAL RESULTS |
Description | Off-white to yellowish crystalline powder | Off-white crystalline powder |
Solubility | Complies | Complies |
Identification | UV: maximum absorption at 235nm and 319nm | Complies |
HPLC: matches the Ref Std spectrum | Complies | |
IR: IR spectrum of sample concordant with Ref Std | Complies | |
Chemical Reaction: should appear red brown spots | Complies | |
pH | 6.5~8.5 | 7.6 |
Related Substances | Impurity A not more than0.5% | 0.05% |
Single Impurity not more than0.1 % | 0.02% | |
Total Impurities not more than 1.0% | 0.08% | |
Strontium Ranelate Ethyl Ester | Not more than 0.2% | Undetected |
Residual Solvents | Aceton not more than 0.5% | Undetected |
Ethanol notmore than 0.5% | Undetected | |
Loss on Drying | 18.0% ~22.0% | 20.11% |
Heavy Metals | ≤0.002% | Complies |
Assay (Calculated on dried basis) | 98.0% ~ 102.0% | 99.6% |
Strontium (Calculated on dried basis) | 30.7~37.8% | 35.1% |
Description:
Strontium ranelate is an antiosteoporotic agent which both increases bone formation and reduces bone resorption, resulting in a rebalance of bone turnover in favor of bone formation. This is similar to the effects of choline-stabilized orthosilicic acid.
Strontium ranelate, a strontium(II) salt of ranelic acid , is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee.The drug is unusual in that it both increases deposition of new bone byosteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA).
Strontium ranelate(S12911) stimulates the calcium sensing receptors (CaSR) and leads to the differentiation of pre-osteoblast to osteoblast which increases the bone formation.IC50 value:Target: CaSRStrontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Strontium Ranelate acts by increasing bone formation and decreasing bone resorption, thus rebalancing bone turnover in favour of bone formation, an effect that results in increased bone mass and strength. Commonly used as an antiosteoporotic. Strontium Ranelate has shown efficacy in preventing early postmenopausal bone loss and reducing the risk of hip fracture in women with postmenopausal osteoporosis.
Function and Application
It is mainly used to treat and prevent osteoporosis in postmenopausal women and significantly reduce the risk of vertebral and hip fractures.
Packing:
FAQ
Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples.
Or if you have special requirement on the goods, we can prepare samples according to your requirement for your confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
Q3: What's the MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10g.
For other low value product, our MOQ starts from 100g and 1kg.
Q4: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by TradeManager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q5: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer.
In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.
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