Product Details:
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Place of Origin: | Xi'an ,China |
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Brand Name: | Wango |
Certification: | ISO 9001, USP, BP |
Model Number: | WG-0026 |
Payment & Shipping Terms:
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Minimum Order Quantity: | 100 gram every time |
Price: | FOB price USD 4000-4200/kilogram, Price can be negotiable freely . |
Packaging Details: | 1kg with double plastic container inside/Aluminum foil bag ; 25kg with double plastic container inside/Fiber drum outside.Or as your request. |
Delivery Time: | 3-5 working days |
Payment Terms: | Western Union, L/C, T/T, MoneyGram |
Supply Ability: | 100 kilogram 0ne month |
Detail Information |
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Appearence: | White Fine Powder | Other Name: | Darifenacin HCL |
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Function: | Urinary System Agents | Cas: | 133099-07-7 |
Product Description
ITEMS |
SPECIFICATION |
TESTRESULTS |
Appearance |
Off-white or white powder |
Conforms |
Identification |
HPLC,NMR;LC-MS |
Conforms |
Related substances |
Individual impurity≤0.5% |
0.09% |
Total impurities≤1.0% |
0.20% |
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Loss on drying |
≤0.5% |
0.3% |
Residue on ignition |
≤0.1% |
0.04% |
Heavy metals |
≤10ppm |
Conforms |
Assay |
≥99.8 % |
99.9% |
Function : Dapfina hydrobromide is used to treat overactive bladder with urge incontinence, urgency, and frequency of urination
Dafenaxine hydrobromide is the first selective muscarinic M3 receptor antagonist developed by Novartis of Switzerland. It was first marketed in the United States in 2005 for the treatment of urinary incontinence, urgency and overactive bladder (OAB). Hydrobromic acid duffy that new alkaline M3 receptor inhibitor for selective a toadstool, M3 receptor leading bladder detrusor contraction, this product is by blocking the M3 receptor to play a role, for the M3 receptor selectivity of 59 times higher than the other receptor subtypes and hydrobromic acid duffy that new does not affect the central nervous system related M1 receptor and M2 receptors associated with cardiovascular function, Therefore, while controlling bladder contraction, there is no cognitive impairment and adverse cardiovascular reactions, and the clinical tolerance is good.
Current clinical used in the treatment of bladder syndrome (OAB) excessive activity of drugs, mainly choline drug resistance in clinical application for many years, effective recognition, but these drugs are more selective, luo certain such as tottenham, or selective low, like the cloth they can not only block the bladder detrusor M3 receptor, can also block other receptor subtypes, For example, M1 receptor affecting cognitive function and M2 receptor affecting cardiac function. Therefore, this drug with low selectivity may produce many adverse reactions when treating OAB. The selectivity of fafenaxine hydrobromide to M3 receptor was 59 times higher than that of other receptor subtypes. Therefore, the effect is significant, the adverse reactions are few, and the clinical tolerance is good.
FAQ
Q1. How does your factory control quality?
All the raw material purchasing and production quality control are strictly following the ISO9001: 2008 management system. Besides, the full-featured detection equipment and GMP quality management system to provide the strongest guarantee for high quality product. We can provide our customers the detailed test report for the quality evaluation before the sample.
Q2. What's your main markets?
North America, Europe, Asia, etc.
Q3. What is your delivery term and delivery period?
We accept FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you. The sample within 3 days, and bulk order within 5 days.
Q4. What is your package?
Powder: PE bag, glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Liquid: glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Bulk order: Fiber drum or steel drum.
Q5. Will you supply samples for test the quality?
We'd like to offer our customers the free samples for the quality evaluation for most products, but the shipping cost is borne by customers.
Q6.What is the payment term?
We can accept TT, DP,LC,Westunion etc.
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