China Pharma Pure Powder manufacturer

Bictegravir 99.99% Active Pharma Ingredients HIV Blocker 1611493-60-7

Product Details:
Place of Origin: Xi'an ,China
Brand Name: Wango
Model Number: WG-0017
Payment & Shipping Terms:
Minimum Order Quantity: 10 gram every time
Price: FOB price USD 5-8/gram, can be negotibale by the quantity .
Packaging Details: 1kg with double plastic container inside/Aluminum foil bag ; 25kg with double plastic container inside/Fiber drum outside.Or as your request.
Delivery Time: 3-5 working days
Payment Terms: Western Union, L/C, T/T, MoneyGram
Supply Ability: 10kilogram 0ne month

Detail Information

Appearence: White Fine Powder Function: HIV Blocker
Cas: 1611493-60-7 Packing: 1-10 Gram
High Light:

99.99% Active Pharma Ingredients


Bictegravir Active Pharma Ingredients



Product Description

HIV Blocker Bictegravir 99.99% fine powder API - Bictegravir 99% Cas1611493-60-7 mafufacturer with top quality from China !

Bictegravir 99.99% Active Pharma Ingredients HIV Blocker 1611493-60-7 0

Product Information :


Product Name



Bictegravir;GS-9883;2,5-Methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide, 2,3,4,5,7,9,13,13a-octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-, (2R,5S,13aR)-;(2R,5S,13aR)-2,3,4,5,7,9,13,13a-Octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide;Bictegravir (GS-9883)









Product Categories

inhibitor, API



Human immunodeficiency virus infection and related diseases are major public health problems worldwide. Human immunodeficiency virus type 1 (HIV-1) encodes three enzymes required for viral replication: reverse transcriptase, protease and integrase. Although they target reverse transcriptase and C, the development of virulent and resistant strains limits their effectiveness. Therefore, new agents that can inhibit HIV replication and minimize PXR activation when co-administered with other drugs are needed. The polycyclic carbamyl pyridinone compound pictilavir has been found to have antiviral activity.

BIC tilavir (BIC), a second-generation integrase chain transfer inhibitor (INSTI), has been approved in combination with emtricitabine and Tenofovir Alafenamide for the treatment of HIV, with effective antiviral activity INSTIs against wild-type virus and first-generation resistant strains in vitro.


Indications :

As part of combination therapy, virologic suppression rates in clinical trials were comparable to first-line combination antiretroviral therapy. Picotilavir has shown a high genetic barrier to the development of in vitro resistance, can be taken with or without food, and bioavailability > 70%. The median plasma half-life is 18 hours, allowing once-daily administration. Picotivir is mainly eliminated from the liver by oxidation of cytochrome P450 3A4 (CYP3A4) and glucuronylation of UDP-glucaldosyltransferase 1A1 (UGT1A1). Therefore, strong inducers of UGT1A1 and CYP3A4 (e.g., rifamycin/anticonvulsant) should be avoided due to the significant reduction in serum exposure to pictilavir. Chelating with polyvalent cation can reduce absorption. Otherwise, drug - to - drug interactions are minimal. Picotilavir was well tolerated. Diarrhea, nausea, and headache were the major adverse reactions associated with it.

Usage :

Bictegravir (BIC) is a new type of integrase inhibitor, a new research drug of integrase inhibitor discovered by scientists. As of June 2016, Bictegravir (BIC) was used as a single-tablet regimen in combination with Tenofovir Alafe Chemicalbooknamide Fumarate (TAF) and Emtricitabine (FTC) for the treatment of HIV-1 infection, BIC/ In the 48-week Phase III clinical trial of FTC/TAF, it was found that it has a high virus inhibition rate, which can inhibit 97% of the virus, and no adverse reactions have been found. It is less toxic to bone and kidney, and may become the most Competitive anti-HIV drugs.





Q1: Are you a manufacturer?

Yes, Wango Biopharm have concentrated on Organic synthesis over 12 years since 2008.
Advanced R&D technology, 380,000 categories chemical reagent are in stock.
Trading products we will serve for you with our ISO supplier system, making your purchasing risk into the lowest.
In addition, we provide the customization service of a new compound from lab to bulk manufacturing.

Q2: How to contact with us?

You can contact with us on Made-in-China, the Average Response Time is 0-4h on Work time, <24h on Non-work time.
For every inquiry, our sales will provide the one-for-one service for you.

Q3:Which kind of payment do you accept?

Normal orders: Company account(The price will be 5%-13% extra discount)
Sample/small orders: Paypal(The 5-10% extra fee),Western Union etc.
About the payment term, we will negotiate alone.

Q4:How to confirm the Product Quality before placing orders?

1st, you can get free samples for some products, just pay the basic cost for us.
2nd,Also you can send the specification or your quest to us, we will customize the products for you.
3rd,We emphasis that our whole company make a living with organic chemical and customers, we absolutely impossible to sale any fake goods, unqualified goods, it is shame! And None False certificate/lie/illegal thing in our sales net!

Q5:How do you treat quality complaint?

The customer complaint handling procedures is the key part in Our ISO management system. We will set up an investigation team for your complaint, and give the handling plan and our corrective and preventive measures within a limited time.


We will refer the MSDS to design the package standard and show you at the PI or Quotation list.
If you want customize package and haven't go against the principle of science, we will do as your request. The cost will be calculate your request.
For dangerous goods, only one style of package, we will do as the UN standard.


We have R&D and manufactured chemicals for 12 years, we have rich experience on Shipping, Many famous companies cooperated with us stably, we are good at shipping all kinds of chemicals.
General goods: The best service, price and lead time.
Dangerous goods: The professional cooperated company, the details please check our website.





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