China Pharma Pure Powder manufacturer

Rhinitis Treatments by Levocetirizine HCL 99% fine powder

Product Details:
Place of Origin: Xi'an ,China
Brand Name: Wango
Certification: USP, BP
Model Number: WG-0029
Payment & Shipping Terms:
Minimum Order Quantity: 1000gram every time
Price: FOB price USD 468-520/kilogram.price can be negotiable freely .
Packaging Details: 1kg with double plastic container inside/Aluminum foil bag ; 25kg with double plastic container inside/Fiber drum outside.Or as your request.
Delivery Time: 3-5 working days
Payment Terms: Western Union, L/C, T/T, MoneyGram
Supply Ability: 1000 kilogram 0ne month

Detail Information

Appearence: White Fine Powder Other Name: Levocetirizine
Function: Allergic Rhinitis Cas: 130018-77-8

Product Description

Levocetirizine Dihydrochloride 99% for Allergic Rhinitis treatments API Powder Pharmaceutical Chemicals manufacturer with top quality from China !

Rhinitis Treatments by Levocetirizine HCL 99% fine powder 0

Product Name

Levocetirizine HCL

CAS No.:



≥ 99.00%


A white,Crystalline Powder or colorless crystals



Molecular Weight




Loss on Drying:


Residue on ignition:


Heavy Metals:


Acidity or Alkalinity:




Readily Carbonizable Substances:


Ordinary Impurities:


What is Levocetirizine hydrochloride?


Levocetirizine hydrochloride is a medication prescribed to treat symptoms of seasonal allergies and hives. These symptoms can include sneezing, a runny nose, and watering eyes, as well as itching and rashes. This antihistamine can help alleviate allergy symptoms by inhibiting the actions of the chemical histamine in the body.


Function of Levocetirizine hydrochloride

[In vivo process] Levo-cetirizine is the levo-body of cetirizine, which has a high binding rate with plasma protein after oral absorption into the blood. The effect of levo-cetirizine is more obvious one hour after oral absorption, and the duration is 24.4 hours, respectively, and the effect reaches its peak within 6 hours after taking the drug. Pharmacokinetic studies confirm that consists of two equal amounts antipodal structure of cetirizine racemic in the body's metabolism without liver, oral cetirizine sinistral 4 hours and 8 hours after plasma concentrations of cetirizine is almost right twice, it's main metabolites in urine, oral 32 hours after 50% - 60% of the drugs by urine excretion, a small amount of waste discharge.


Cetirizine 】 【 pharmacological mechanism sinistral developed by Belgium UCB company, with the SuoFei that, desloratadine, b fluorine lamictal is listed as the third generation of anti-allergic drugs, such as because of cetirizine is left-handed, so pharmacological effects similar to those of cetirizine, but fewer side effects, cetirizine had mild inhibitory effect on central nervous system, Research shows that cetirizine inhibition of the central nervous system is mainly the right body has certain affinity with related receptors in the brain, so a single optical isomer of cetirizine cetirizine - left-handed cetirizine avoided ably to central nervous system side effects such as sedation, sleepiness, antihistamine activity is similar to cetirizine. Levocetirizine has a stronger anti-allergic effect than other anti-allergic drugs because of its extensive pharmacological mechanism. In addition to its strong antagonistic effect against H1 receptor, it also has other anti-allergic mechanisms. The pharmacological mechanisms associated with asthma include inhibition of the aggregation and infiltration of inflammatory cells mainly composed of eosinophils in the airway, inhibition of the degranulation of hypertrophic/basophils, inhibition of delayed asthmatic response, and enhancement of the bronchodilation of β 2-adrenergic receptor agonists.


In order to study the curative effect of cetirizine enantiomorphism structure, in healthy adult volunteers used cetirizine, cetirizine left-handed and right-handed cetirizine (Ucb28557) on skin allergic reaction caused by histamine, randomized, double-blind and cross experiment results show that cetirizine and cetirizine sinistral of histamine induced skin rash and flush has significant inhibitory effect, The antihistamine activity of 2.5mg levo-cetirizine was superior to that of 5mg cetirizine, suggesting that the efficacy of levo-cetirizine was superior to that of cetirizine, while dexcetirizine showed no antagonistic effect against H1 receptors.


[Clinical Application] As a third-generation antihistamine, Levistirizine was marketed in February 2001. It is a single optical isomer of the second-generation antihistamine cetirizine, which is mainly used for the treatment of allergic diseases in respiratory system, skin and eyes, such as allergic rhinoconjunctivitis, allergic skin disease, allergic asthma, etc. It has the advantages of fast effect, strong and lasting effect and few side effects.


[Usage and dose] The usual clinical dose for adults is 5mg, once a day.


[Side effects] No central nervous system side effects such as sedation and drowsiness; No arrhythmia-inducing effect of second generation antihistamines (e.g. Terfenadine, asimidazole, etc.) was observed.


[Notes] It is applicable to a wide range of people, and can be used for pregnant and lactating women. It is classified as class B (relatively safe) for pregnant women by FDA of the United States. It is also safe for children (including infants) in clinical use.




Q1: Are you a manufacturer?

Yes, Wango Biopharm have concentrated on Organic synthesis over 12 years since 2008.
Advanced R&D technology, 380,000 categories chemical reagent are in stock.
Trading products we will serve for you with our ISO supplier system, making your purchasing risk into the lowest.
In addition, we provide the customization service of a new compound from lab to bulk manufacturing.

Q2: How to contact with us?

You can contact with us on Made-in-China, the Average Response Time is 0-4h on Work time, <24h on Non-work time.
For every inquiry, our sales will provide the one-for-one service for you.

Q3:Which kind of payment do you accept?

Normal orders: Company account(The price will be 5%-13% extra discount)
Sample/small orders: Paypal(The 5-10% extra fee),Western Union etc.
About the payment term, we will negotiate alone.

Q4:How to confirm the Product Quality before placing orders?

1st, you can get free samples for some products, just pay the basic cost for us.
2nd,Also you can send the specification or your quest to us, we will customize the products for you.
3rd,We emphasis that our whole company make a living with organic chemical and customers, we absolutely impossible to sale any fake goods, unqualified goods, it is shame! And None False certificate/lie/illegal thing in our sales net!

Q5:How do you treat quality complaint?

The customer complaint handling procedures is the key part in Our ISO management system. We will set up an investigation team for your complaint, and give the handling plan and our corrective and preventive measures within a limited time.


We will refer the MSDS to design the package standard and show you at the PI or Quotation list.
If you want customize package and haven't go against the principle of science, we will do as your request. The cost will be calculate your request.
For dangerous goods, only one style of package, we will do as the UN standard.


We have R&D and manufactured chemicals for 12 years, we have rich experience on Shipping, Many famous companies cooperated with us stably, we are good at shipping all kinds of chemicals.
General goods: The best service, price and lead time.
Dangerous goods: The professional cooperated company, the details please check our website.



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