China Pharma Pure Powder manufacturer

Darifenacin Hydrobromide API Active Pharmaceutical Ingredient Cas 133099-07-7

Product Details:
Place of Origin: Xi'an ,China
Brand Name: Wango
Certification: ISO 9001, USP, BP
Model Number: WG-0026
Payment & Shipping Terms:
Minimum Order Quantity: 100 gram every time
Price: FOB price USD 4000-4200/kilogram, Price can be negotiable freely .
Packaging Details: 1kg with double plastic container inside/Aluminum foil bag ; 25kg with double plastic container inside/Fiber drum outside.Or as your request.
Delivery Time: 3-5 working days
Payment Terms: Western Union, L/C, T/T, MoneyGram
Supply Ability: 100 kilogram 0ne month

Detail Information

Appearence: White Fine Powder Other Name: Darifenacin HCL
Function: Urinary System Agents Cas: 133099-07-7
High Light:

Darifenacin API Active Pharmaceutical Ingredient

,

133099-07-7

Product Description

Darifenacin Hydrobromide 99.9% Cas133099-07-7 Urinary System Agents Pharmaceutical Chemicals manufacturer Powder with top quality from China !

Darifenacin Hydrobromide API Active Pharmaceutical Ingredient Cas 133099-07-7 0

ITEMS

SPECIFICATION

TESTRESULTS

Appearance

Off-white or white powder

Conforms

Identification

HPLC,NMR;LC-MS

Conforms

Related substances

Individual impurity≤0.5%

0.09%

Total impurities≤1.0%

0.20%

Loss on drying

≤0.5%

0.3%

Residue on ignition

≤0.1%

0.04%

Heavy metals

≤10ppm

Conforms

Assay

99.8 %

99.9%

 

[Dosage form and specification] Sustained-release tablets, 7.5mg, 15mg

[Indication]

Dapfina hydrobromide is used to treat patients with bladder overactivity (OAB) with urge incontinence, urgency and frequency of urination.

[Project Introduction]

Dafenaxine hydrobromide is the first selective muscarinic M3 receptor antagonist developed by Novartis of Switzerland. It was first marketed in the United States in 2005 for the treatment of urinary incontinence, urgency and overactive bladder (OAB). Hydrobromic acid duffy that new alkaline M3 receptor inhibitor for selective a toadstool, M3 receptor leading bladder detrusor contraction, this product is by blocking the M3 receptor to play a role, for the M3 receptor selectivity of 59 times higher than the other receptor subtypes and hydrobromic acid duffy that new does not affect the central nervous system related M1 receptor and M2 receptors associated with cardiovascular function, Therefore, while controlling bladder contraction, there is no cognitive impairment and adverse cardiovascular reactions, and the clinical tolerance is good.

Current clinical used in the treatment of bladder syndrome (OAB) excessive activity of drugs, mainly choline drug resistance in clinical application for many years, effective recognition, but these drugs are more selective, luo certain such as tottenham, or selective low, like the cloth they can not only block the bladder detrusor M3 receptor, can also block other receptor subtypes, For example, M1 receptor affecting cognitive function and M2 receptor affecting cardiac function. Therefore, this drug with low selectivity may produce many adverse reactions when treating OAB. The selectivity of fafenaxine hydrobromide to M3 receptor was 59 times higher than that of other receptor subtypes. Therefore, the effect is significant, the adverse reactions are few, and the clinical tolerance is good.

[Preparation process] This product is a sustained-release tablet, which is a patented new technology independently developed by our company. The preparation process has high feasibility and good reproducibility, and has obtained the invention patent.

 

 

FAQ

 

Q1: Are you a manufacturer?


Yes, Wango Biopharm have concentrated on Organic synthesis over 12 years since 2008.
Advanced R&D technology, 380,000 categories chemical reagent are in stock.
Trading products we will serve for you with our ISO supplier system, making your purchasing risk into the lowest.
In addition, we provide the customization service of a new compound from lab to bulk manufacturing.


Q2: How to contact with us?


You can contact with us on Made-in-China, the Average Response Time is 0-4h on Work time, <24h on Non-work time.
For every inquiry, our sales will provide the one-for-one service for you.


Q3:Which kind of payment do you accept?


Normal orders: Company account(The price will be 5%-13% extra discount)
Sample/small orders: Paypal(The 5-10% extra fee),Western Union etc.
About the payment term, we will negotiate alone.


Q4:How to confirm the Product Quality before placing orders?


1st, you can get free samples for some products, just pay the basic cost for us.
2nd,Also you can send the specification or your quest to us, we will customize the products for you.
3rd,We emphasis that our whole company make a living with organic chemical and customers, we absolutely impossible to sale any fake goods, unqualified goods, it is shame! And None False certificate/lie/illegal thing in our sales net!


Q5:How do you treat quality complaint?


The customer complaint handling procedures is the key part in Our ISO management system. We will set up an investigation team for your complaint, and give the handling plan and our corrective and preventive measures within a limited time.

Q6:Package


We will refer the MSDS to design the package standard and show you at the PI or Quotation list.
If you want customize package and haven't go against the principle of science, we will do as your request. The cost will be calculate your request.
For dangerous goods, only one style of package, we will do as the UN standard.


Q7:Shipping


We have R&D and manufactured chemicals for 12 years, we have rich experience on Shipping, Many famous companies cooperated with us stably, we are good at shipping all kinds of chemicals.
General goods: The best service, price and lead time.
Dangerous goods: The professional cooperated company, the details please check our website.

 

 

 

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