China Pharma Pure Powder manufacturer

API Adefovir Dipivoxil Raw Powder For Chronic Hepatitis B Cas 142340-99-6

Product Details:
Place of Origin: Xi'An, China
Brand Name: Wango
Certification: GMP
Model Number: W-273
Payment & Shipping Terms:
Minimum Order Quantity: 10 gram for every time by Express
Price: FOB price 1180-1250/kg base on 1kg MOQ
Packaging Details: 100-1000 gram small bag ,with 25kg drum ,or as your requirements
Delivery Time: within 2 days
Payment Terms: L/C, T/T, Western Union, T/T
Supply Ability: 200kilogram for every month

Detail Information

Name: Adefovir Dipivoxil Cas: 142340-99-6
Function: Chronic Hepatitis B
High Light:

API Adefovir Dipivoxil

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Cas 142340-99-6 Adefovir Dipivoxil

Product Description

Adefovir Dipivoxil Cas 142340-99-6 Raw Powder For Chronic Hepatitis B

 

API Adefovir Dipivoxil Raw Powder For Chronic Hepatitis B Cas 142340-99-6 0

 

Item Specification Result
Appearance white to off-white powder Complies
Related substance (HPLC) Total impurity ≤0.5%
Max single impurity ≤0.1%
0.2%
0.06%
Odor Characteristic Complies
Assay 99% 99.8%
Sieve analysis 100% pass 80 mesh Complies
Loss on Drying
Residue on Ignition
≤1.0%
≤1.0%
0.12%
0.09%
Heavy Metal <10ppm Complies
As <0.1ppm 0.05ppm
Pb <0.1ppm 0.05ppm
Cd <0.1ppm 0.05ppm
Residual Solvents <100ppm Complies

 

Description:

Adefovir is an orally active prodrug that is indicated for thetreatment of the chronic form of hepatitis B. The dipivoxil moieties are hydrolyzed by ubiquitous esterases to yieldadefovir, which is phosphorylated by adenylate kinase toyield adefovir diphosphate. This compound is inhibitory atHBV DNA polymerase. In addition, adefovir undergoes incorporationinto viral DNA and causes chain termination.Adefovir is poorly absorbed by the oral route, but the dipivoxilester groups cause the bioavailability to increase toapproximately 60%.

Usage:

Has a broad spectrum of antiviral activity, can be used for the treatment of chronic hepatitis B.

 

 

API Adefovir Dipivoxil Raw Powder For Chronic Hepatitis B Cas 142340-99-6 1

 

 

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