Product Details:
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Place of Origin: | Xi'An, China |
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Brand Name: | Wango |
Certification: | GMP |
Model Number: | W-273 |
Payment & Shipping Terms:
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Minimum Order Quantity: | 10 gram for every time by Express |
Price: | FOB price 1180-1250/kg base on 1kg MOQ |
Packaging Details: | 100-1000 gram small bag ,with 25kg drum ,or as your requirements |
Delivery Time: | within 2 days |
Payment Terms: | L/C, T/T, Western Union, T/T |
Supply Ability: | 200kilogram for every month |
Detail Information |
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Name: | Adefovir Dipivoxil | Cas: | 142340-99-6 |
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Function: | Chronic Hepatitis B | ||
Highlight: | API Adefovir Dipivoxil,Cas 142340-99-6 Adefovir Dipivoxil |
Product Description
Adefovir Dipivoxil Cas 142340-99-6 Raw Powder For Chronic Hepatitis B
Item | Specification | Result |
Appearance | white to off-white powder | Complies |
Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
Odor | Characteristic | Complies |
Assay | 99% | 99.8% |
Sieve analysis | 100% pass 80 mesh | Complies |
Loss on Drying Residue on Ignition |
≤1.0% ≤1.0% |
0.12% 0.09% |
Heavy Metal | <10ppm | Complies |
As | <0.1ppm | 0.05ppm |
Pb | <0.1ppm | 0.05ppm |
Cd | <0.1ppm | 0.05ppm |
Residual Solvents | <100ppm | Complies |
Description:
Adefovir is an orally active prodrug that is indicated for thetreatment of the chronic form of hepatitis B. The dipivoxil moieties are hydrolyzed by ubiquitous esterases to yieldadefovir, which is phosphorylated by adenylate kinase toyield adefovir diphosphate. This compound is inhibitory atHBV DNA polymerase. In addition, adefovir undergoes incorporationinto viral DNA and causes chain termination.Adefovir is poorly absorbed by the oral route, but the dipivoxilester groups cause the bioavailability to increase toapproximately 60%.
Usage:
Has a broad spectrum of antiviral activity, can be used for the treatment of chronic hepatitis B.
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