China Pharma Pure Powder manufacturer

Bambuterol Hcl Pharma Pure Powder , Bronchial Asthma Treatment 81732-46-9

Product Details:
Place of Origin: Xi'an ,China
Brand Name: Wango
Certification: ISO 9001, USP, BP
Model Number: WG-0029
Payment & Shipping Terms:
Minimum Order Quantity: 1000gram every time
Price: FOB price USD 1180-1280/kilogram, can be negotiable freely .
Packaging Details: 1kg with double plastic container inside/Aluminum foil bag ; 25kg with double plastic container inside/Fiber drum outside.Or as your request.
Delivery Time: 3-5 working days
Payment Terms: Western Union, L/C, T/T, MoneyGram
Supply Ability: 1000 kilogram 0ne month

Detail Information

Appearence: White Crystal Powder Other Name: Bambuterol
Function: Bronchial Asthma Treatment Cas: 81732-46-9
High Light:

bambuterol hcl Pharma Pure Powder

,

Pharma Bronchial Asthma Treatment

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81732-46-9 Bronchial

Product Description

Bambuterol Hydrochloride 99% Cas 81732-46-9 anti-Asthmatic Agents API Powder Pharmaceutical Chemicals manufacturer with top quality from China !

Bambuterol Hcl Pharma Pure Powder , Bronchial Asthma Treatment 81732-46-9 0

Items

Standards

Results

Appearance

White or off-white solid powder

Complies

Identification

By IR

Complies

By HPLC

Complies

Solubility

Soluble in DMF, sparingly soluble in THF, slightly soluble in methanol and acetonitrile, very sightly soluble in ethanol and dichloromethane, insoluble in water

Complies

Polymorphic Form

Polymorphic form 1

Complies

Melting Point

211ºC~216ºC

212.8ºC~214.9ºC

Water Content

0.50%

0.10%

Heavy Metals

20ppm

Complies

Residue on Ignition

0.20%

0.09%

Related Substance

Any single impurity: 0.10%

0.06%

Total Impurities: 1.00%

0.16%

Assay (on the anhydrous basis)

98.0%~102.0%

99.94%

Particle Size

D90: 100µm

Complies

Reference Standard

In-house Standard

Conclusion

The product complied to In-house standard.

Storage

Preserve in tight,light-resistant containers in a cool place

Usage and dosage :

Take it orally once before going to bed every night. The initial dose for adults is 10mg, which can be increased to 20mg after 1-2 weeks according to the clinical effect. An initial dose of 5.0mg is recommended for patients with renal insufficiency (GFR50ml/ min).

 

Clinical research :

 

[Functions and indications] bronchial asthma, chronic asthmatic bronchitis, obstructive emphysema and other pulmonary diseases with bronchospasm.

 

[Chemical composition] The main ingredient of this product is Benbuterol hydrochloride.

 

Pharmacological Action This product is the prodrug of terbutaline, a selective β2 receptor agonist, which is metabolized into terbutaline under the action of enzyme after oral absorption. Terbutaline mainly activates the β2 receptor of the bronchial smooth muscle, thereby relaxing the bronchial smooth muscle. In addition, this product can inhibit the release of inflammatory mediators by mast cells. Toxicity of repeated administration :Wistar rats and Beagle dogs were orally given 108mg/Kg/ day and 34.42mg/Kg/ day for 90 consecutive days, respectively. No toxic reaction was observed in animal behavior, diet, hematology, blood biochemistry, gross anatomy and histopathological examination of major organs. Genotoxicity :Ames test, CHL cell chromosome aberration test and NIH mouse bone marrow micronucleus test results were negative. Reproductive toxicity: the dose of this product was 180mg/Kg/ day, and it was given orally for 10 consecutive days. No obvious toxic reaction was observed in Wistar pregnant rats, and no obvious appearance, visceral and skeletal malformations were observed in fetal offspring.

 

[Drug interaction] Bambuterol hydrochloride may prolong the muscle relaxation effect of succincholine because bambuterol hydrochloride partially inhibits the production of cholinesterase, which is dose-dependent and can be fully restored.

 

[Adverse reactions] The side effects that have been found include tremor, headache, tonic muscle spasm and palpitations, which are common characteristics of oral bronchodilators. However, the adverse reaction of this drug is mild compared with other similar drugs. The intensity of side effects was positively correlated with dose, and most of them disappeared spontaneously within the first 1-2 weeks of treatment. A very few people may appear mildly elevated transaminase and dry mouth, dizziness, stomach discomfort, etc.

 

Contraindications: This product, terbutaline and sympathomimetic amine allergy is contraindicated.

 

 

Why Choose Us?

 

1. High-concentration products, strictly control the quality.
2. Reasonable and flexible price matched with high quality.
3. Spot samples can be shipped quickly after payment, saving time for receiving goods.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Safe raw materials from China.
6. Have professional customs clearance capabilities and the best after-sales service.


Our Service

 

1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast.
4.Quick and clear response to customers questions.
5.We could make our price discount if you place a substantial order with us.
6.Products can be packaged according to customer requirements.


F.A.Q

1:Can I get some samples before bulk order?


Most products provide free samples, but the shipping cost be paid by customers.

2: What's your MOQ?


For the high value product, our MOQ starts from 10g,100g and 1kg.

3: Which kind of payment terms do you accept?


PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union, L/C, Alibaba trade assurance, Cashapp,Moneygram or Bitcoin.

4.How to place an order?


You can contact me through Trademanager, WhatsApp, Skype Online and other contact methods, tell me the product and quantity you need, and then we will give you a quote. If you choose one of the above payment methods, we will arrange the delivery for you.

5:How about your delivery time?


A: Generally, it will take 3 to 5 days after receiving your advance payment.

6:How do you treat quality complaint?


A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

 

 

Bambuterol Hcl Pharma Pure Powder , Bronchial Asthma Treatment 81732-46-9 1

 

 

 

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