China Pharma Pure Powder manufacturer

99% Sex Enhancement Powder , Erectile Dysfunction Vardenafil 224785-90-4

Product Details:
Place of Origin: Xi'an ,China
Brand Name: Wango
Certification: USP, BP
Model Number: WG-0053
Payment & Shipping Terms:
Minimum Order Quantity: 100gram every time by Express
Price: FOB price USD 800-880/kilogram ,price can be negotiable freely .
Packaging Details: 1kg with double plastic container inside/Aluminum foil bag ; 25kg with double plastic container inside/Fiber drum outside.Or as your request.
Delivery Time: 3-5 working days
Payment Terms: L/C, T/T, Western Union, MoneyGram
Supply Ability: 1000kilogram / 0ne month

Detail Information

Name: Vardenafil Function: Erectile Dysfunction Treatmants
Cas: 224785-90-4 Other Name: Sildenafil
High Light:

99% Sex Enhancement Powder

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Vardenafil Sex Enhancement Powder

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224785-90-4 Vardenafil

Product Description

Man Erectile Dysfunction Treatmants Of Vardenafil 99% Cas224785-90-4 not exceed 20mg per day

99% Sex Enhancement Powder , Erectile Dysfunction Vardenafil 224785-90-4 0

Product Name Vardenafil
Synonyms VARD ENAFIL,HYDROCHLORIDE SALT
Nuviva
Vivanza
Varde nafil HCl
Varde nafil (hydrochloride)
Levitra,Vald enafil
1-((3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethylpipe razine Hydrochloride
2-{2-Ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-onhydrochlorid
2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1)
Imidazo[5,1-f][1,2,4]triazin-4(1H)-one, 2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propyl-, hydrochloride (1:1)
pipe razine, 1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-, monohydrochloride
VAR DENAFIL
VARD ENAFILMONOHYDROCHLORIDE(SUBJECTTOPATENTFREE)
Levitra
4-{[4-ethoxy-3-(4-hydroxy-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)phenyl]sulfonyl}-1-ethylpiperazin-1-ium chloride
Levitra,Valdenafil.HCl
2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride
Var denafil hydrochloride
2-{2-éthoxy-5-[(4-éthylpipérazin-1-yl)sulfonyl]phényl}-5-méthyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one chlorhydrate
CAS NO 224785-91-5
ENIENCS 200-835-2
Molecular Formula C23H33ClN6O4S
Molecular Weight 525.064
Melting point 214-216ºC
Boiling Point 692.2ºC at 760 mmHg
Flash Point 372.5ºC
Density N/A
Assay 99%
Grade Pharmaceutical Grade
Solubility N/A
Appearance White to off-white crystalline solid


99% Sex Enhancement Powder , Erectile Dysfunction Vardenafil 224785-90-4 1

 

Description:
 

The pharmacological properties of vardenafil are type 5 phosphodiesterase retarder. In other words, vardenafil's key mechanism of action is to block a chemical called phosphodiesterase 5 in the body. Type 5 phosphodiesterase is in essence an enzyme, with microbial catalytic reaction, hydrolysis reaction activity. These enzymes are generally dispersed in the surface of the sarcoplasmic reticulum of the capillaries of the cavernosum of the male, and adjust the blood volume in the capillaries of the cavernosum of the penis according to the catalytic reaction and hydrolysis reaction activity. Against ED patients, phosphodiesterase type 5 beings, can be on the same position of signal transduction molecules cause hydrolysis, impact signal transduction molecule structure on the propagation of the corpora cavernosa capillary effect, and further reduce the human body blood supply of corpora cavernosa, reduce the delay time corpora cavernosa blood, corpus cavernosum caused by not enough blood supply. O cut it as a phosphodiesterase type 5 retarding agent, competing can suppress phosphodiesterase type 5, different level land block phosphodiesterase type 5 the hydrolysis reaction of signal transduction molecule structure, practiced a lot can enlarge the molecular structure of signal transduction of corpora cavernosa capillaries, and ensure reasonable corpus cavernosum blood vessels expand, Increase blood supply to capillaries of penile cavernosa and prevent ED.

Advantages, if compared with sildenafil, tadalafil, and avanafil  ?

Like vardenafil, sildenafil, tadalafil, and avanafil are also PDE5 retardants with pharmacological properties. In other words, vardenafil works in much the same way as the other three PDE5 retardants. Although the treatment of ED works similarly, the pharmacokinetics of vardenafil differ from those of the other three PDE5 retarders because the chemical structure of the drugs differs from each other. Drug pharmacokinetics is scientific research in the digestion and absorption, and across the metabolism and metabolic regularity, and applied mathematics principle, the way of the drug in the blood density and time correlation, is an evaluation of drugs for the treatment of diseases efficacy, efficacy, and its drug absorption and metabolism of key indexes to body harm. According to the pharmacokinetic studies of vardenafil, which is a highly selective PDE5 retarder, vardenafil permeates the blood at a faster rate than sildenafil and tadalafil, and can be effective as soon as 10 minutes faster. In comparison, sildenafil and tadalafil must take at least 30 to 1 hour to be effective. Other studies have shown that vardenafil can significantly increase the concentration of signal transduction molecular structure (cGMP) in male sponges, increase the efficacy time of signal transduction molecular structure to soften blood vessels, and promote the expansion of penile cavernous vascular sarcoplasmic reticulum more reasonably. Pharmacokinetic research shows that when vardenafil treated usage after take orally, half-life do 3 nmol/L can in the penis sponge body suggesting a good cGMP cumulative effect, and the same conditions, sildenafil is need nearly 30 nmol/L half-life, suggesting that vardenafil to promote the effect of the corpora cavernosa sarcoplasmic reticulum left ventricular is very strong. In addition to the advantages of the main pharmacokinetic parameters, there are many references and experimental scientific studies in the world that show that vardenafil has a better therapeutic effect for some patients with refractory ED. According to the scientific research on male scientific journal of the Chinese nation the latest progress of vardenafil treatment of intractable ED "and" vardenafil used in intractable ED people "shows that the merge of vardenafil for abnormal is disease and high blood pressure, diabetes patients after resection of the prostate surgery, trauma, cervical spinal injury and sildenafil useless ED patients, It also showed good tolerance and safety factor.

How to take ?

 

Vardenafil is currently approved by the UK FDA in two forms: orally disintegrating tablets and plain plastic coated tablets. Among them, only one treatment of oral disintegrating tablets was 10mg/ tablet. And general plastic film sugar-coated tablets have three kinds of medical use, respectively 5mg/ tablet, 10mg/ tablet and 20mg/ tablet. The biggest difference between oral disintegrating tablets and ordinary plastic film sugar coated tablets is the way they are taken. Oral disintegrating tablets must be taken on the tongue, depending on the chewing position By oral cavity and digestive system mucous membrane digestion and absorption, to prevent tap water after swallowing must go through the digestive tract digestion and absorption into the liver, so bypass the liver first effect, faster. Scientific studies have shown that 10mg vardenafil tablet has better leakage in human body after digestion and absorption compared with 10mg vardenafil ordinary plastic film coating. Vardenafil tablet has not been sold for commercial circulation in China due to the approval of procedures. Vardenafil is a general plastic film coated tablet, approved by the State Drug and Drug Administration in 2004, which has been used in clinical medicine for nearly 15 years. According to foreign literature reports, multi-core, randomized controlled scientific studies and meta-scientific studies in China, vardenafil in 3 doses has accurate safety factor and efficacy in the treatment of ED. Among the three dosages, 5mg/ tablet vardenafil is the least dosages. Clinically, the lowest dose of vardenafil is strongly recommended for those aged 65 years or older, because pharmacological studies have shown that vardenafil clearance rates are significantly lower in patients over 65 years of age, with an increase in dispersive blood concentration of approximately 52% compared with younger healthy subjects. Therefore, it is proposed that vardenafil should be taken as a priority for those aged 65 years or older with a gradual increase in dosage from 5mg. For the majority of ED men under 65 years of age, 10mg/ tablet vardenafil is strongly recommended for start-end treatment. Vardenafil at 10mg is strongly recommended to be used once daily. Clinically, for most young, middle-aged and elderly ED patients, if all liver and kidney functions are normal, it is suggested that the dosage of vardenafil should be gradually selected from 10mg/ time/day. Although 10mg of vardenafil is strongly recommended for the majority of ED patients, for some patients with unique assessment, prominent ED symptoms and poor efficacy of 10mg of vardenafil, if the liver and kidney functions are normal and there are no significant cardiovascular and cerebrovascular problems, The higher dosage of vardenafil can be increased to 20mg per dose, but the greater dosage should not exceed 20mg per day



Our Service

 

1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast.
4.Quick and clear response to customers questions.
5.We could make our price discount if you place a substantial order with us.
6.Products can be packaged according to customer requirements.


F.A.Q

1:Can I get some samples before bulk order?
Most products provide free samples, but the shipping cost be paid by customers.

2: What's your MOQ?
For the high value product, our MOQ starts from 10g,100g and 1kg.

3: Which kind of payment terms do you accept?
PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union, L/C, Alibaba trade assurance, Cashapp,Moneygram or Bitcoin.

4.How to place an order?
You can contact me through WhatsApp, Skype Online and other contact methods, tell me the product and quantity you need, and then we will give you a quote. If you choose one of the above payment methods, we will arrange the delivery for you.

5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.

6:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.


 

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