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(ITEMS )
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( STANDARDS )
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Appearance
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Light yellowish Crystalline powder
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Solubility
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Water
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Slightly soluble
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Sparingly soluble
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Ethanol (96%)
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Very slightly soluble
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Identification -IR Spectrum
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Concordant with the spectrum of reference substance
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Absorbance
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≤0.20
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Related substances (%)
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Impurity C, D, E
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≤0.2%
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Impurity A, B
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≤0.1%
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Unspecified Impurities
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≤0.2%
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Total Impurity
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≤0.5%
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Heavy metal
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≤20ppm
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Loss on drying
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≤0.5%
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Sulphated ash
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≤0.10%
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Assay(on the dried basis):
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99.2%-99.5%
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Mbofloxacin is a fungicide and its fungicidal activity is concentration-dependent. Sensitive bacteria can die 20 ~ 30rain after exposure. Like other fluoroquinolones, mbofloxacin has shown significant post-antibiotic effects on both Gram-negative and gram-positive bacteria and has activity on both quiescent and growing stages of bacterial replication. Its mechanism of action is not fully understood, but it is thought to work by inhibiting bacterial DNA cyclotron enzyme (type II topoisomerase), preventing DNA superhelix formation and DNA synthesis. Mbofloxacin and other veterinary commercial fluoroquinolones have similar antimicrobial activity profiles. These drugs for most gram-negative bacillus and staphylococcus aureus has the very good activity, including pseudomonas aeruginosa, klebsiella Chemicalbook bacterium, Mr Bush's e. coli, enterococcus, campylobacter genus, shigella, salmonella, aeromonas, haemophilus, deformation bacteria, Yale sen bacteria, vibrio genera, etc. Most of the species and strains. Other commonly susceptible species include Brucella, Chlamydia trachomatis, staphylococcus (including penicillin-producing and methicillin-resistant bacteria), chlamydia and mycobacteria. Fluoroquinolones have varying activity against most streptococci and are not generally recommended for the treatment of infections in this genus. These drugs are less active against most anaerobic bacteria and are not effective in treating anaerobic infections. Drug-resistant strains have emerged as a result of variation, notably pseudomonas, Klebsiella pneumoniae, acinetobacter and enterococcus, but plasmid-mediated resistance is generally considered to be rare .
Function of Marbofloxacin
Fluoroquinolones are used for the treatment of deep and superficial skin infections, urinary tract infections in dogs, skin and soft tissue infections in cats, acute upper respiratory tract infections.
Used for respiratory tract, digestive tract, urinary tract and skin infection caused by sensitive bacteria in cattle, pigs, dogs and cats. There is also a whitlow effect on bovine and sheep mastitis and pig mastitis - hysteritis - agalactia syndrome.
Body dosage period: 6 days for cows, 1.5 days for milk waste; The pig .
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Advanced R&D technology, 250,000 categories chemical reagent are in stock.
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