China Pharma Pure Powder manufacturer

Brivaracetam 99% Api Active Pharmaceutical Anti Epilepsy Cas 357336-20-0

Product Details:
Place of Origin: Xi'an ,China
Brand Name: Wango
Certification: ISO 9001, USP, BP
Model Number: WG-0060
Payment & Shipping Terms:
Minimum Order Quantity: 100gram every time
Price: FOB price USD 715-750/kilogram, can be negotiable .
Packaging Details: 1kg with double plastic container inside/Aluminum foil bag ; 25kg with double plastic container inside/Fiber drum outside.Or as your request.
Delivery Time: 3-5 working days
Payment Terms: Western Union, L/C, T/T, MoneyGram
Supply Ability: 50 kilogram 0ne month

Detail Information

Appearence: White Fine Powder Other Name: Levetiracetam
Function: Anti-Epilepsy Cas: 357336-20-0
High Light:

Brivaracetam Api Active Pharmaceutical

,

Api Active Pharmaceutical Anti Epilepsy

,

Brivaracetam 357336-20-0

Product Description

Brivaracetam Anti-Epilepsy above16 years older 99% Cas 357336-20-0 API manufacturer with top quality from China !

Brivaracetam 99% Api Active Pharmaceutical Anti Epilepsy Cas 357336-20-0 0

Items

Standards

Results

Appearance

White or off-white crystalline powder

Complies

Identification

By IR

Complies

 

By HPLC

Complies

Specific Optical Rotation
(MeOH,c=1.0g/100mL)

-61.0°~- 64.0°

-62.2°

Water Content(KF)

1.00%

0.09%

Heavy Metals

≤20ppm

Complies

Residue on Ignition

≤0.10%

0.05%

Residual Solvents(GC)

Tert-Butyl methyl ether: 5000ppm

440ppm

Related Substances

Sum of (R,R-isomer and S,S-isomer): 0.30%

0.05%

 

Related compound 1: 0.10%

ND

 

Other maximum single impurities: 0.10%

0.01%

 

Total impurities: 1.00%

0.05%

Related Substance
Chiral(HPLC)

R,R-Isomer: 0.15%

0.01%

 

R,S-Isomer: 0.15%

0.02%

 

S,S-Isomer: 0.30%

0.03%

Assay
(HPLC basis on drying)

98.0%~102.0%

99.98%

Reference Standard

In-house Standard

Conclusion

The product complied to In-house standard.

Storage

Preserve in tight,light-resistant containers in a cool place

 

【 Drug alias 】 : Brivaracetam

 

【 British name 】 : Briviact

 

[R&D Company] : UCB, Inc

 

[Application] : It is suitable for the treatment of partial epileptic epilepsy in patients with epilepsy aged 16 years and above as adjunctive therapy.

 

[Indications and uses]

 

BRIVIACT is indicated as adjunctive therapy for the treatment of partial seizure epilepsy in patients 16 years of age and older who have epilepsy.

 

[Dosage and administration]

 

⑴ The recommended starting dose is 50 mg twice daily. The dose may be adjusted downward to 25 mg twice daily (50 mg daily) or to 100 mg twice daily (200 mg daily), depending on individual patient tolerability and treatment response.

 

⑵ BRIVIACT injection may be used when oral administration is transient and not feasible.

 

⑶ Liver damage: for all stages of liver damage, the recommended starting dose is 25 mg twice daily; The maximum dose is 75 mg twice daily.

 

[Dosage form and specification]

 

⑴ Tablets: 10 mg, 25 mg, 50 mg, 75 mg, and 100 mg

 

⑵ Oral solution: 10 mg/mL

 

⑶ Injection: 50 mg/5 mL single dose vials

 

[Contraindication]

 

Any hypersensitivity to buiscitan or the inactive ingredient in BRIVIACT.

 

[Warnings and Precautions]

 

Suicidal behavior and ideation: Monitor patients for suicidal behavior and ideation.

 

Neurological side effects: monitor for drowsiness and fatigue, and advise patients not to drive or operate machinery until they have had sufficient experience with BRIVIACT.

 

Psychiatric adverse reactions: Behavioral reactions include psychiatric symptoms, irritability, depression, aggressive behavior, and anxiety; Monitor the patient for symptoms.

 

Hypersensitivity: bronchospasm and angioedema: Notify client to seek immediate medical attention. Do not start BRIVIACT again if hypersensitivity is terminated.

 

Antiepileptic withdrawal: BRIVIACT should be withdrawn gradually.

 

[Adverse reactions]

 

The most common adverse reactions (at least 5% for BRIVIACT and at least 2% more frequently than placebo) were drowsiness/sedation, dizziness, fatigue, and nausea/vomiting.

 

Report suspected adverse reactions, contact UCB, Inc., call 844-599-2273 or call 1-800 - the FDA FDA - 1088 or http://www.fda.gov/medwatch.

 

[Drug interaction]

 

(1) Rifampin: An increase in the dose of BRIVIACT in patients with Rifampin is recommended because of the reduced concentration of BRIVIACT.

 

⑵ Carbamazepine: reduction of Carbamazepine dose in BRIVIACT patients should be considered because of increased exposure to Carbamazepine metabolites, if tolerance problems arise.

 

(3) Phenytoin: Because concentrations of Phenytoin may increase, and Phenytoin levels should be monitored in patients taking BRIVIACT.

 

(4) Levetiracetam: When combined with Levetiracetam, BRIVIACT did not increase therapeutic benefit.

 

【 Used in special groups 】

 

Pregnancy: possible risk to the fetus based on animal data.

 

[Medication for pregnant women]

 

It is not known whether BRIVIACT is excreted in human milk. Excretion of buisetam in breast milk has been shown in rat studies.

 

Because many drugs are excreted into human milk, a decision should be made whether to discontinue breastfeeding or BRIVIACT, considering the importance of the drug to the mother.

 

【 Medication for children 】

 

The safety and efficacy of BRIVIACT has not been established in patients younger than 16 years of age

 

 

Why Choose Us?

 

1. High-concentration products, strictly control the quality.
2. Reasonable and flexible price matched with high quality.
3. Spot samples can be shipped quickly after payment, saving time for receiving goods.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Safe raw materials from China.
6. Have professional customs clearance capabilities and the best after-sales service.

 

Our Service


1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast.
4.Quick and clear response to customers questions.
5.We could make our price discount if you place a substantial order with us.
6.Products can be packaged according to customer requirements.

F.A.Q1:Can I get some samples before bulk order?
Most products provide free samples, but the shipping cost be paid by customers.

 

2: What's your MOQ?


For the high value product, our MOQ starts from 10g,100g and 1kg.

 

3: Which kind of payment terms do you accept?


PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union, L/C, Alibaba trade assurance, Cashapp,Moneygram or Bitcoin.

 

4.How to place an order?


You can contact me through Trademanager, WhatsApp, Skype Online and other contact methods, tell me the product and quantity you need, and then we will give you a quote. If you choose one of the above payment methods, we will arrange the delivery for you.

 

5:How about your delivery time?


A: Generally, it will take 3 to 5 days after receiving your advance payment.

 

6: How do you treat quality complaint?


A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

 

 

Brivaracetam 99% Api Active Pharmaceutical Anti Epilepsy Cas 357336-20-0 1

 

 

 

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