2000kg Marbofloxacin In Cats Treat Susceptible Bacteria Cas 115550-35-1

Function of Marbofloxacin

Marbofloxacin, like other fluoroquinolones, is used to treat susceptible bacteria in a variety of species. It is approved for use in dogs and cats in the United States, and in other species outside the U.S. Infections treated with marbofloxacin include skin and soft tissue infections, bone infections, urinary tract infections (UTIs), pneumonia, and infections caused by intracellular organisms.

Marbofloxacin has been effective for some blood-borne pathogens such as Mycoplasma haemofelis in cats at a dose of 2.75 mg/kg q24h PO for 14 days. Marbofloxacin also has been used in horses to treat infections caused by susceptible bacteria. In dogs, the half-life is 7-9 hours, but it has been longer in some studies. In horses, the half-life has varied from 4.7-7.6 hours, depending on the study. Volume of distribution in these species is 1.2-2 L/kg. Oral absorption is close to 100% in small animals and approximately 60% in horses. In cattle the half-life is 5-9 hours in calves and 4-7 hours in ruminants. In preruminant calves oral absorption is approximately 100%. In sows the half-life is 8-10 hours and oral absorption is 80%. In young pigs the half-life is 13 hours. In calves, it has been used to treat respiratory infections (bovine respiratory disease [BRD]) at 2 mg/kg for 3-5 days, or a single dose administered once at 8-10 mg/kg (see regulatory restrictions). In sows it is used to treat Mastitis-Metritis-Agalactia (MMA) syndrome. In pigs, doses of 2 mg/kg and higher reached the therapeutic targets for swine respiratory disease pathogens.

Dosage : 

Intramuscular injection of 2mg per 1kg body weight of cattle and pigs once a day

Orally administered 2mg per LKG body weight of livestock once a day

[Preparation and Specification] Mbofloxacin tablets (1)5mg (2)20mg (3)80mg

Mbofloxacin injection lmL: 100mg

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