99% USP36 Pure Ivermectin Powder Anti Intestinal Parasites Cas 70288-86-7

Product Description

Ivermectin 99% USP36 anti-intestinal parasites Raw Powder Cas 70288-86-7 manufacturer for pets and vets and human !

COA  

What  the Ivermectin  is ?

Ivermectin has good effect and safety on nematodes, insects, ticks and other parasites when used in small doses. Launched in 1981, it was quickly used in animal husbandry around the world to protect against nematodes and other infections. It was registered for human use in 1987 and was immediately donated for the treatment of onchocerciasis and lymphatic filariasis. Since its launch, the massive drug donation program has helped 1.5 billion people. The latest figures show that around 186 million people worldwide still need treatment each year, and around 112 million have access to drugs, mainly in the African region.

Ivermectin is a Food and Drug Administration (FDA)-approved antiparasitic drug that is used to treat several neglected tropical diseases, including onchocerciasis, helminthiases, and scabies.1 It is also being evaluated for its potential to reduce the rate of malaria transmission by killing mosquitoes that feed on treated humans and livestock.2 For these indications, ivermectin has been widely used and is generally well tolerated.1,3 Ivermectin is not approved by the FDA for the treatment of any viral infection.

Application 

Reports from in vitro studies suggest that ivermectin acts by inhibiting the host importin alpha/beta-1 nuclear transport proteins, which are part of a key intracellular transport process that viruses hijack to enhance infection by suppressing the host’s antiviral response.4,5 In addition, ivermectin docking may interfere with the attachment of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to the human cell membrane.6 Ivermectin is thought to be a host-directed agent, which may be the basis for its broad-spectrum activity in vitro against the viruses that cause dengue, Zika, HIV, and yellow fever.4,7-9 Despite this in vitro activity, no clinical trials have reported a clinical benefit for ivermectin in patients with these viruses. Some studies of ivermectin have also reported potential anti-inflammatory properties, which have been postulated to be beneficial in people with COVID-19.10-12

Some observational cohorts and clinical trials have evaluated the use of ivermectin for the prevention and treatment of COVID-19. Data from some of these studies .

In the past 30 years, ivermectin has played an outstanding role in the fight against parasitic diseases, saving millions of lives, which is a glorious page of the modern pharmaceutical industry. With the rapid development of medical technology, parasitic diseases, bacterial infections and viral infections have been controlled. At present, cancer, cardiovascular and cerebrovascular diseases, diabetes and other chronic diseases have become the primary factors threatening human health. In order to cope with the dilemma, biotechnology advances rapidly, and various new antibody drugs spring up like mushrooms. As we carefully develop new drugs, let's not forget the old ones, such as ivermectin, which have shown extraordinary promise in many disease domains. The new use of old medicine may also be a new way of medical innovation.

Recommendation :

• There is insufficient evidence for the COVID-19 Treatment Guidelines Panel (the Panel) to recommend either for or against the use of ivermectin for the treatment of COVID-19. Results from adequately powered, well-designed, and well-conducted clinical trials are needed to provide more specific, evidence-based guidance on the role of ivermectin in the treatment of COVID-19.