China Pharma Pure Powder manufacturer

Anti Gout Allopurinol Powder 315-30-0 For Hyperuricemia Treatment

Product Details:
Place of Origin: Xi'An,China
Brand Name: wango
Certification: USP 39
Model Number: W-0086
Payment & Shipping Terms:
Minimum Order Quantity: 25kilogram every time
Price: FOB price 60-68usd/kg , can be Negotiable .
Packaging Details: 25kilogram /drum
Delivery Time: 3-5 working days
Payment Terms: L/C, T/T, Western Union
Supply Ability: 1000kilogram every month

Detail Information

Other Name: Zyloprim Function: Hyperuricemia Treatment
Cas: Cas 315-30-0 State: White Fine Powder
High Light:

Hyperuricemia Allopurinol Powder

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315-30-0 Allopurinol

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Hyperuricemia allopurinol anti gout

Product Description

 Antigout Allopurinol 99% Cas 315-30-0 China bigggest manufacturer supply 1000kilogram fresh stock !

 

Anti Gout Allopurinol Powder 315-30-0 For Hyperuricemia Treatment 0

Chemical Name

allopurinol

Synonyms

AL-100;Pural;1H-Pyrazolo[3,4-d]pyrimidin-4(5H)-one;Apurin;4-HPP;Expand

CAS No.

315-30-0

Molecular Formula

C5H4N4O

Molecular Weight

136.11100

PSA

74.43000

LogP

-0.35380

Properties

Appearance & Physical State

White to Off-White Solid

Density

1.89g/cm3

Boiling Point

290.8ºC at 760 mmHg

Melting Point

350ºC

Flash Point

129.7ºC

Refractive Index

1.816

Water Solubility

0.35 g/L (25 ºC)

Stability

Stable under normal temperatures and pressures.

Storage Condition

Store in a tightly closed container. Store in a cool, dry area away from incompatible substances.

 

 

 

What is  allopurinol  ?

 

Allopurinol, its metabolites can inhibit xanthine oxidase, so that hypoxanthine and xanthine cannot be converted into uric acid, that is, the synthesis of uric acid is reduced, thereby reducing the concentration of uric acid in the blood and reducing the presence of urate in bone , Joints and kidneys, drugs that can inhibit the synthesis of uric acid. This product can inhibit the activity of liver drug enzymes.

 

Function & Application

1. Allopurinol can effectively offset the adverse harm caused by hyperuricemia.
2. Allopurinol is an effective preparation for treating old myocardial infarction and improving left ventricular function.
3. Treatment of non-bacterial prostatitis Non-bacterial prostatitis caused by urine reflux of the prostate, the urine level in the prostatic fluid is significantly increased, and the main symptoms of prostatitis are relieved.

 

[Usage and dosage]

 

1. Adults often take orally. ① Treatment of gout, 0.1g once, 2-3 times a day; Or 0.3g once, once a day; In order to reduce the onset of acute gout, the initial dosage was 0.1g per day, and gradually increased until the serum uric acid concentration approached 6mgJ100ml. The maximum daily dosage should not exceed 0.3g. Because this product metabolite oxypurinol is excreted by the kidney, the dosage of renal insufficiency can be reduced according to the creatinine clearance rate. The daily dosage of creatinine clearance rate is 0.2g when 10 -- 20ml per minute, 0.1g when 3 -- 10ml per minute, 0.1g when less than 3ml per minute, and 0.1g every 24 hours or more. ② Treatment of kidney stones, 0.1 -- 0.2g, 1 -- 4 times a day; Or 0.3g once, once a day.

 

2. Children often take oral dosage. Limited for secondary hyperuricemia of malignant tumors, 50mg once within 6 years old, 3 times a day; From 6 to 10 years old, 100mg once, three times a day, or 300mg once a day. After 48 hours of administration, dosage should be adjusted according to patient response.

 

Folding preparations and specifications

Allopurinol tablets 0.1g

 

(1) For reducing the concentration of uric acid in the blood, orally, 50mg each time,2-3 times a day, the dose increases gradually,2-3 weeks later, up to 0.2-0.4g a day, divided into 2-3 times. Maintenance dose 0.1-0.2g each time, 2-3 times a day. (2) for uric acid calculi, orally 0.1-0.2g each time, 4 times a day, or 300mg once a day.

 

1. Treatment of gout: the initial dose of 0.05g each time, 2-3 times a day, increased to 0.2 ~ 0.4g a day after 2 ~ 3 weeks, divided into 2 ~ 3 times; Severe gout can be used up to 0.6g per day. Children 8mg/kg daily. Maintenance dose: 0.1-0.2g for adults, 2-3 times a day.

 

2. Treatment of secondary hyperuricemia: the general dose is 0.1 ~ 0.6g per day, divided into 2 ~ 3 times. For patients with hyperuricemia and leukemia, the initial dose was 0.2g, 3 times a day. Maintenance dose 0.3-0.4 g per day, divided.

 

3. Treatment of major epilepsy: on the basis of using original antiepileptic drugs, take 0.3g of this product in the afternoon every day (0.15g for children under 10 years old every day).

 

This product can induce acute gout and increase the frequency and severity of acute gout, so it should be combined with low dose colchicine in the first 4 to 8 weeks.

 

Take the period should drink more water, and make urine neutral or alkaline to facilitate uric acid excretion. At the same time, it is advisable to eat a low purine diet, and should be taken after meals to reduce gastric irritation.

 

 

Anti Gout Allopurinol Powder 315-30-0 For Hyperuricemia Treatment 1

 

 

 

 

 

 

 

 

 

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