wango Zyloprim Allopurinol For Arthritis Of White Solid powder

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Properties

What is allopurinol?

Allopurinol reduces the production of uric acid in the body. Uric acid buildup can lead to gout or kidney stones.

Allopurinol is used to treat gout or kidney stones.

Allopurinol is also used to decrease levels of uric acid in people who are receiving cancer treatment.

How does allopurinol work?

Allopurinol helps reduce urate levels in your blood (serum urate) and reduces gout attacks.

Uric acid is a normal product of your metabolism and in the blood, uric acid becomes urate. When urate levels are high, crystals can form around joints causing inflammation, pain and damage. This is known as gout.

To reduce gout attacks, it is important to keep your serum urate level below 0.36 mmol/L. When the serum urate is below 0.36mmol/L no new crystals form and crystals that are in your joints or skin can dissolve. Read more about gout.

Dosage information

Usual Adult Dose of Allopurinol for Gout:

Dose will vary with the severity of the disease:

Initial dose: 100 mg orally once a day
-Increase in increments of 100 mg weekly until a serum uric level of 6 mg/dL or less is attained

Mild Gout:
-Average maintenance dose: 200 to 300 mg orally once a day
Moderately Severe Tophaceous Gout:
-Average maintenance dose: 400 to 600 mg orally/day in divided doses
Minimal Effective Dose: 100 to 200 mg per day
Maximum Dose: 800 mg per day

Comments:
-Oral doses in excess of 300 mg/day should be given in divided doses, preferably after meals to minimize gastric irritation.
-A gradual dose titration is recommended to reduce the possibility of acute gouty attacks.
-Normal serum urate levels are usually achieved in 1 to 3 weeks.

Use: For the management of patients with signs and symptoms of primary or secondary gout (acute attacks, tophi, joint destruction, uric acid lithiasis, and/or nephropathy).