Cas 57852-57-0 Idarubicin HCL 99% Acuting Non Lymphocytic Leukemia

Product Description

Idarubicin Hydrochloride 99.99% Cas 57852-57-0 acute non-lymphocytic leukemia manufacturer of China !

What is  idarubicin ?

Doxorubicin epirubicin, idarubicin and valrubicin are structurally related cytotoxic antineoplastic antibiotics used in the therapy of several forms of lymphoma, leukemia, sarcoma and solid organ cancers. Doxorubicin is associated with a high rate of transient serum enzyme during therapy and to rare instances of clinically apparent acute liver injury with jaundice that can be severe and even fatal. Epirubicin and idarubicin have similar profiles of activity and adverse events as doxorubicin, but have been less commonly used and their potential for causing liver injury has been less well defined. Valrubicin is instilled directly in the bladder as treatment of refractory urinary bladder cancer, has little systemic distribution, and has not been associated with serum enzyme elevations or clinically apparent liver injury.

Idarubicin is a semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA replication, RNA transcription and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds.

Warning of the Application :

1. Idarubicin Hydrochloride Injection should be given slowly into a freely flowing intravenous infusion. It must never be given intramuscularly or subcutaneously. Severe local tissue necrosis can occur if there is extravasation during administration.

2. As is the case with other anthracyclines the use of Idarubicin Hydrochloride can cause myocardial toxicity leading to congestive heart failure. Cardiac toxicity is more common in patients who have received prior anthracyclines or who have pre-existing cardiac disease.

3. As is usual with antileukemic agents, severe myelosuppression occurs when Idarubicin hydrochloride is used at effective therapeutic doses.

4. It is recommended that Idarubicin hydrochloride be administered only under the supervision of a physician who is experienced in leukemia chemotherapy and in facilities with laboratory and supportive resources adequate to monitor drug tolerance and protect and maintain a patient compromised by drug toxicity. The physician and institution must be capable of responding rapidly and completely to severe hemorrhagic conditions and/or overwhelming infection.

5. Dosage should be reduced in patients with impaired hepatic or renal function .

FAQ : 

Q1: How to confirm the Product Quality before placing orders?

A. Offering you our products specification standard (tested by HPLC, UV, GC and TLC etc.)

B. Free samples could be sent to check the product quality before ordering.

C. If you have special requirement on the product, we may customize it according to your requirement until to your approval.

Q2: Samples & MOQ

A. We could provide some free samples, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.

B. For the high value product, our MOQ starts from 1g and generally starts from 10g.

For other low value product, our MOQ starts from 1kg.

Q3: How about delivery?

A: Delivery lead time: within 3 days when get the payment.

B. Samples: please expect 5-7 days by FedEx,EMS, UPS,TNT.

Orders: please allow 5-8 days by Air, 20-35 days by Sea

Why Choose Us?

1. High-concentration products, strictly control the quality.
2. Reasonable and flexible price matched with high quality.
3. Spot samples can be shipped quickly after payment, saving time for receiving goods.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Safe raw materials from China.
6. Have professional customs clearance capabilities and the best after-sales service.

Our Service

1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast.
4.Quick and clear response to customers questions.
5.We could make our price discount if you place a substantial order with us.
6.Products can be packaged according to customer requirements.

F.A.Q1:Can I get some samples before bulk order?
Most products provide free samples, but the shipping cost be paid by customers.

2: What's your MOQ?

For the high value product, our MOQ starts from 10g,100g and 1kg.

3: Which kind of payment terms do you accept?

PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union, L/C, Alibaba trade assurance, Cashapp,Moneygram or Bitcoin.

4.How to place an order?

You can contact me through Trademanager, WhatsApp, Skype Online and other contact methods, tell me the product and quantity you need, and then we will give you a quote. If you choose one of the above payment methods, we will arrange the delivery for you.

5:How about your delivery time?

A: Generally, it will take 3 to 5 days after receiving your advance payment.

6: How do you treat quality complaint?

A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.